Product overview:

Carrier-free (BSA/glycerol-free) CFLAR mouse monoclonal antibody, clone LBI2H3

Field of research:

Apoptosis

Summary:

The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists. [provided by RefSeq, Feb 2011]

Alternative names:

c-FLIP; c-FLIPL; c-FLIPR; c-FLIPS; CASH; CASP8AP1; Casper; CLARP; FLAME; FLAME-1; FLAME1; FLIP

Species reactivity:

Human

Host:

Mouse

Target:

CFLAR

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 1-272 of human CFLAR(NP_003870) produced in E.coli.

Clone:

LBI2H3

Conjugation:

Unconjugated

Gene name:

Homo sapiens CASP8 and FADD like apoptosis regulator (CFLAR), transcript variant 1, mRNA.

Symbol:

CFLAR

Pathway:

Apoptosis

Function:

Druggable Genome, Protease

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:500

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com