Product overview:

Carrier-free (BSA/glycerol-free) UFD1L mouse monoclonal antibody, clone LBI4C7

Field of research:

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Summary:

The protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18. [provided by RefSeq, Jun 2009]

Alternative names:

UFD1

Species reactivity:

Human

Host:

Mouse

Target:

UFD1

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human UFD1L (NP_005650) produced in E.coli.

Clone:

LBI4C7

Conjugation:

Unconjugated

Gene name:

Homo sapiens ubiquitin recognition factor in ER associated degradation 1 (UFD1), transcript variant 1, mRNA.

Symbol:

UFD1

Pathway:

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Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000, IHC 1:150

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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