Product overview:

Carrier-free (BSA/glycerol-free) TFB1M mouse monoclonal antibody, clone LBI10H8

Field of research:

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Summary:

The protein encoded by this gene is a dimethyltransferase that methylates the conserved stem loop of mitochondrial 12S rRNA. The encoded protein also is part of the basal mitochondrial transcription complex and is necessary for mitochondrial gene expression. The methylation and transcriptional activities of this protein are independent of one another. Variations in this gene may influence the severity of aminoglycoside-induced deafness (AID). [provided by RefSeq, Aug 2010]

Alternative names:

CGI-75; CGI75; mtTFB; mtTFB1

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

TFB1M

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 116-346 of human TFB1M (NP_057104) produced in E.coli.

Clone:

LBI10H8

Conjugation:

Unconjugated

Gene name:

Homo sapiens transcription factor B1, mitochondrial (TFB1M), transcript variant 1, mRNA; nuclear gene for mitochondrial product.

Symbol:

TFB1M

Pathway:

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Function:

Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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