Product overview:

Carrier-free (BSA/glycerol-free) SPA17 mouse monoclonal antibody, clone LBI2G6

Field of research:

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Summary:

This gene encodes a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22. [provided by RefSeq, Jan 2009]

Alternative names:

CT22; SP17; SP17-1

Species reactivity:

Human

Host:

Mouse

Target:

SPA17

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human SPA17 (NP_059121) produced in E.coli.

Clone:

LBI2G6

Conjugation:

Unconjugated

Gene name:

Homo sapiens sperm autoantigenic protein 17 (SPA17), mRNA.

Symbol:

SPA17

Pathway:

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Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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