Product overview:

Arginase-1(ARG1) mouse monoclonal antibody, clone UMLBI288

Field of research:

Arginine and proline metabolism, Metabolic pathways

Summary:

Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].

Alternative names:

arginase, liver; arginase 1; liver-type arginase; OTTHUMP00000017209; type I arginase

Species reactivity:

Mouse, Rat

Host:

Mouse

Target:

ARG1

Isotype:

IgG2a

Immunogen:

Full length human recombinant protein of human ARG1 (NP_000036) produced in HEK293T cell.

Clone:

UMLBI288

Conjugation:

Unconjugated

Gene name:

Homo sapiens arginase 1 (ARG1), transcript variant 2, mRNA.

Symbol:

ARG1

Pathway:

Arginine and proline metabolism, Metabolic pathways

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com