Product overview:

PTH mouse monoclonal antibody,clone UMLBI274

Field of research:

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Summary:

This gene encodes a member of the parathyroid family of proteins. The encoded preproprotein is proteolytically processed to generate a protein that binds to the parathyroid hormone/parathyroid hormone-related peptide receptor and regulates blood calcium and phosphate levels. Excess production of the encoded protein, known as hyperparathyroidism, can result in hypercalcemia and kidney stones. On the other hand, defective processing of the encoded protein may lead to hypoparathyroidism, which can result in hypocalcemia and numbness. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]

Alternative names:

FIH1; PTH1

Species reactivity:

Human

Host:

Mouse

Target:

PTH

Isotype:

IgG2b

Immunogen:

Human recombinant protein fragment corresponding to amino acids 32-115 of human PTH (NP_000306) produced in E.coli.

Clone:

UMLBI274

Conjugation:

Unconjugated

Gene name:

Homo sapiens parathyroid hormone (PTH), transcript variant 1, mRNA.

Symbol:

PTH

Pathway:

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Function:

Druggable Genome, Secreted Protein

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.5~1.0 mg/ml (Lot Dependent)

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

IHC 1:4000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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