Product overview:

GEMIN8 mouse monoclonal antibody,clone UMLBI185

Field of research:

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Summary:

The protein encoded by this gene is part of the SMN complex, which is necessary for spliceosomal snRNP assembly in the cytoplasm and pre-mRNA splicing in the nucleus. The encoded protein binds to both SMN1 and the GEMIN6/GEMIN7 heterodimer, mediating their interaction. This protein is found in nuclear Gemini of Cajal bodies (gems) and in the cytoplasm. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010]

Alternative names:

FAM51A1

Species reactivity:

Human

Host:

Mouse

Target:

GEMIN8

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human GEMIN8 (NP_060326) produced in E.coli.

Clone:

UMLBI185

Conjugation:

Unconjugated

Gene name:

Homo sapiens gem nuclear organelle associated protein 8 (GEMIN8), transcript variant 3, mRNA.

Symbol:

GEMIN8

Pathway:

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Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.5~1.0 mg/ml (Lot Dependent)

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

IHC 1:100~400

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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