Product overview:

HMBS mouse monoclonal antibody,clone UMLBI144

Field of research:

Metabolic pathways, Porphyrin and chlorophyll metabolism

Summary:

This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Alternative names:

PBG-D; PBGD; PORC; UPS

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

HMBS

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human HMBS (NP_000181) produced in HEK293T cell.

Clone:

UMLBI144

Conjugation:

Unconjugated

Gene name:

Homo sapiens hydroxymethylbilane synthase (HMBS), transcript variant 1, mRNA.

Symbol:

HMBS

Pathway:

Metabolic pathways, Porphyrin and chlorophyll metabolism

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.5~1.0 mg/ml (Lot Dependent)

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:200

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com