Product overview:

Desmin mouse monoclonal antibody,clone UMLBI166

Field of research:

Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)

Summary:

This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. [provided by RefSeq, Jul 2008]

Alternative names:

CSM1; CSM2; LGMD2R

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

DES

Isotype:

IgG1

Immunogen:

Full length human recombiant protein of human DES(NP_001918) produced in E.coli.

Clone:

UMLBI166

Conjugation:

Unconjugated

Gene name:

Homo sapiens desmin (DES), transcript variant 1, mRNA.

Symbol:

DES

Pathway:

Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.5~1.0 mg/ml (Lot Dependent)

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

IHC 1:200

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com