Product overview:

ALDH1L1 mouse monoclonal antibody, clone UMLBI43

Field of research:

One carbon pool by folate

Summary:

The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]

Alternative names:

10-fTHF; 10-FTHFDH; FDH; FTHFD

Species reactivity:

Human, Monkey, Mouse, Rat, Dog

Host:

Mouse

Target:

ALDH1L1

Isotype:

IgG2b

Immunogen:

Full length human recombinant protein of human ALDH1L1 (NP_036322) produced in HEK293T cell.

Clone:

UMLBI43

Conjugation:

Unconjugated

Gene name:

Homo sapiens aldehyde dehydrogenase 1 family member L1 (ALDH1L1), transcript variant 2, mRNA.

Symbol:

ALDH1L1

Pathway:

One carbon pool by folate

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.5~1.0 mg/ml (Lot Dependent)

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500, IHC 1:400, IF 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com