Product overview:

XPF mouse monoclonal antibody,clone UMLBI20

Field of research:

Nucleotide excision repair

Summary:

The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6).

Alternative names:

ERCC11; FANCQ; RAD1; XFEPS; XPF

Species reactivity:

Human, Monkey, Mouse, Rat, Dog

Host:

Mouse

Target:

ERCC4

Isotype:

IgG2a

Immunogen:

Full length human recombinant protein of human XPF (NP_005227) produced in HEK293 cell.

Clone:

UMLBI20

Conjugation:

Unconjugated

Gene name:

Homo sapiens ERCC excision repair 4, endonuclease catalytic subunit (ERCC4), mRNA.

Symbol:

ERCC4

Pathway:

Nucleotide excision repair

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.5~1.0 mg/ml (Lot Dependent)

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500~2000, IF 1:100, FLOW 1:100, IHC1:500

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com