Product overview:

SERPINB4 mouse monoclonal antibody, clone UMLBI16

Field of research:

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Summary:

SERPINB4 is also called squamous cell carcinoma antigen 2 (SCCA-2) or leupin. It directly inhibits human granzyme proteolytic activity and that overexpression of SERPINB4 in HeLa cells inhibits recombinant granzyme-induced as well as NK cell-mediated cell death.

Alternative names:

LEUPIN; PI11; SCCA-2; SCCA1; SCCA2

Species reactivity:

Human

Host:

Mouse

Target:

SERPINB4

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human SERPINB4 (NP_002965) produced in HEK293T cell.

Clone:

UMLBI16

Conjugation:

Unconjugated

Gene name:

Homo sapiens serpin family B member 4 (SERPINB4), transcript variant 1, mRNA.

Symbol:

SERPINB4

Pathway:

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Function:

Druggable Genome, Secreted Protein

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

0.5~1.0 mg/ml (Lot Dependent)

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500, IHC 1:150, IF 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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