Product overview:

COL6A1 mouse monoclonal antibody,clone LBI1G8

Field of research:

ECM-receptor interaction, Focal adhesion

Summary:

The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy. [provided by RefSeq, Jul 2008]

Alternative names:

BTHLM1; OPLL; UCHMD1

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

COL6A1

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 752-835 of human COL6A1 (NP_001839) produced in E.coli.

Clone:

LBI1G8

Conjugation:

Unconjugated

Gene name:

collagen type VI alpha 1

Symbol:

COL6A1

Pathway:

ECM-receptor interaction, Focal adhesion

Function:

Request info at info@sobekbio.com

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com