Product overview:

SSTR5 mouse monoclonal antibody,clone LBI1E4

Field of research:

Neuroactive ligand-receptor interaction

Summary:

Somatostatin and its related peptide cortistatin exert multiple biological actions on normal and tumoral tissue targets by interacting with somatostatin receptors (SSTRs). The protein encoded by this gene is one of the SSTRs, which is a multi-pass membrane protein and belongs to the G-protein coupled receptor 1 family. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase, and different regions of this receptor molecule are required for the activation of different signaling pathways. A mutation in this gene results in somatostatin analog resistance. Alternatively spliced transcript variants have been identified in this gene. [provided by RefSeq, Feb 2010]

Alternative names:

SS-5-R

Species reactivity:

Human

Host:

Mouse

Target:

SSTR5

Isotype:

IgG2c

Immunogen:

Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human SSTR5(NP_001044). The exact sequence is proprietary.

Clone:

LBI1E4

Conjugation:

Unconjugated

Gene name:

somatostatin receptor 5

Symbol:

SSTR5

Pathway:

Neuroactive ligand-receptor interaction

Function:

Druggable Genome, GPCR, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com