Product overview:

DEDD mouse monoclonal antibody,clone LBI7C9

Field of research:

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Summary:

This gene encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Alternative names:

CASP8IP1; DEDD1; DEFT; FLDED1; KE05

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

DEDD

Isotype:

IgG2a

Immunogen:

Human recombinant protein fragment corresponding to amino acids 1-318 of human DEDD (NP_127491) produced in E.coli.

Clone:

LBI7C9

Conjugation:

Unconjugated

Gene name:

death effector domain containing

Symbol:

DEDD

Pathway:

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Function:

Druggable Genome, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

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