Product overview:

PTF1A mouse monoclonal antibody,clone LBI5E5

Field of research:

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Summary:

This gene encodes a protein that is a component of the pancreas transcription factor 1 complex (PTF1) and is known to have a role in mammalian pancreatic development. The protein plays a role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. The protein is thought to be involved in the maintenance of exocrine pancreas-specific gene expression including elastase 1 and amylase. Mutations in this gene cause cerebellar agenesis and loss of expression is seen in ductal type pancreas cancers. [provided by RefSeq, Jul 2008]

Alternative names:

bHLHa29; PACA; PAGEN2; PTF1-p48

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

PTF1A

Isotype:

IgG2b

Immunogen:

Full length human recombinant protein of human PTF1A (NP_835455) produced in E.coli.

Clone:

LBI5E5

Conjugation:

Unconjugated

Gene name:

pancreas specific transcription factor, 1a

Symbol:

PTF1A

Pathway:

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Function:

Embryonic stem cells, ES Cell Differentiation/IPS

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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