Product overview:

HOXD8 mouse monoclonal antibody,clone LBI1E3

Field of research:

Request info at info@sobekbio.com

Summary:

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. In addition to effects during embryogenesis, this particular gene may also play a role in adult urogenital tract function. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]

Alternative names:

HOX4; HOX4E; HOX5.4

Species reactivity:

Human, Mouse

Host:

Mouse

Target:

HOXD8

Isotype:

IgG2a

Immunogen:

Human recombinant protein fragment corresponding to amino acids 69-290 of human HOXD8 (NP_062458) produced in E.coli.

Clone:

LBI1E3

Conjugation:

Unconjugated

Gene name:

homeobox D8

Symbol:

HOXD8

Pathway:

Request info at info@sobekbio.com

Function:

ES Cell Differentiation/IPS, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500~2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com