Product overview:

ARHGEF18 mouse monoclonal antibody,clone LBI4B5

Field of research:

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Summary:

Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008]

Alternative names:

P114-RhoGEF

Species reactivity:

Human

Host:

Mouse

Target:

ARHGEF18

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 118-215 of human ARHGEF18 (NP_001124427) produced in E.coli.

Clone:

LBI4B5

Conjugation:

Unconjugated

Gene name:

Rho/Rac guanine nucleotide exchange factor 18

Symbol:

ARHGEF18

Pathway:

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Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500~2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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