Product overview:

IL-17A mouse monoclonal antibody, clone LBI3H2

Field of research:

Cytokine-cytokine receptor interaction

Summary:

The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Jul 2008]

Alternative names:

CTLA-8; CTLA8; IL-17; IL-17A; IL17; ILA17

Species reactivity:

Human

Host:

Mouse

Target:

IL17A

Isotype:

IgG2b

Immunogen:

Human recombinant protein fragment corresponding to amino acids 24-155 of human IL-17A (NP_002181) produced in E.coli.

Clone:

LBI3H2

Conjugation:

Unconjugated

Gene name:

interleukin 17A

Symbol:

IL17A

Pathway:

Cytokine-cytokine receptor interaction

Function:

Druggable Genome, Secreted Protein

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

ELISA 1:5000-10000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

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