Product overview:

NGAL mouse monoclonal antibody, clone LBI10C8

Field of research:

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Summary:

This gene encodes a protein that belongs to the lipocalin family. Members of this family transport small hydrophobic molecules such as lipids, steroid hormones and retinoids. The protein encoded by this gene is a neutrophil gelatinase-associated lipocalin and plays a role in innate immunity by limiting bacterial growth as a result of sequestering iron-containing siderophores. The presence of this protein in blood and urine is an early biomarker of acute kidney injury. This protein is thought to be be involved in multiple cellular processes, including maintenance of skin homeostasis, and suppression of invasiveness and metastasis. Mice lacking this gene are more susceptible to bacterial infection than wild type mice. [provided by RefSeq, Sep 2015]

Alternative names:

24p3; MSFI; NGAL; p25

Species reactivity:

Human

Host:

Mouse

Target:

LCN2

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 21-198 of human NGAL (NP_005555) produced in E.coli.

Clone:

LBI10C8

Conjugation:

Unconjugated

Gene name:

lipocalin 2

Symbol:

LCN2

Pathway:

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Function:

Secreted Protein

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

ELISA 1:5000-10000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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