Product overview:

TNFRSF17 mouse monoclonal antibody, clone LBI3H5

Field of research:

Cytokine-cytokine receptor interaction

Summary:

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008]

Alternative names:

BCM; BCMA; CD269; TNFRSF13A

Species reactivity:

Human

Host:

Mouse

Target:

TNFRSF17

Isotype:

IgG1

Immunogen:

Recombinant full length protein of human TNFRSF17/BCMA (NP_001183) produced in HEK293 cell.

Clone:

LBI3H5

Conjugation:

Unconjugated

Gene name:

tumor necrosis factor receptor superfamily member 17

Symbol:

TNFRSF17

Pathway:

Cytokine-cytokine receptor interaction

Function:

Druggable Genome, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

FC 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com