Product overview:

NAPSA mouse monoclonal antibody, clone LBI8A5

Field of research:

Lysosome

Summary:

This gene encodes a member of the peptidase A1 family of aspartic proteases. The encoded preproprotein is proteolytically processed to generate an activation peptide and the mature protease. The activation peptides of aspartic proteinases function as inhibitors of the protease active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The encoded protease may play a role in the proteolytic processing of pulmonary surfactant protein B in the lung and may function in protein catabolism in the renal proximal tubules. This gene has been described as a marker for lung adenocarcinoma and renal cell carcinoma. [provided by RefSeq, Feb 2016]

Alternative names:

KAP; Kdap; NAP1; NAPA; SNAPA

Species reactivity:

Human

Host:

Mouse

Target:

NAPSA

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 64-244 of human NAPSA (NP_004842) produced in E.coli.

Clone:

LBI8A5

Conjugation:

Unconjugated

Gene name:

napsin A aspartic peptidase

Symbol:

NAPSA

Pathway:

Lysosome

Function:

Druggable Genome, Protease

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

IHC 1:500

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

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