Product overview:

MICB mouse monoclonal antibody, clone LBI4E9

Field of research:

Natural killer cell mediated cytotoxicity

Summary:

This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

Alternative names:

PERB11.2

Species reactivity:

Human

Host:

Mouse

Target:

MICB

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human MICB (NP_005922) produced in HEK293T cell.

Clone:

LBI4E9

Conjugation:

Unconjugated

Gene name:

MHC class I polypeptide-related sequence B

Symbol:

MICB

Pathway:

Natural killer cell mediated cytotoxicity

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:1000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com