Product overview:

EIF2AK2 mouse monoclonal antibody,clone LBI3F5

Field of research:

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Summary:

The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Alternative names:

EIF2AK1; LEUDEN; PKR; PPP1R83; PRKR

Species reactivity:

Human

Host:

Mouse

Target:

EIF2AK2

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 51-191 of human EIF2AK2 (NP_001129123) produced in E.coli.

Clone:

LBI3F5

Conjugation:

Unconjugated

Gene name:

eukaryotic translation initiation factor 2 alpha kinase 2

Symbol:

EIF2AK2

Pathway:

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Function:

Druggable Genome, Protein Kinase, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500, IHC 1:500

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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