Product overview:

SOX2 mouse monoclonal antibody,clone LBI1H9

Field of research:

Request info at info@sobekbio.com

Summary:

This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq, Jul 2008]

Alternative names:

ANOP3; MCOPS3

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

SOX2

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 135-317 of human SOX2 (NP_003097) produced in E.coli.

Clone:

LBI1H9

Conjugation:

Unconjugated

Gene name:

SRY-box 2

Symbol:

SOX2

Pathway:

Request info at info@sobekbio.com

Function:

Adult stem cells, Cancer stem cells, Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com