Product overview:

PDZK1 mouse monoclonal antibody,clone LBI2B4

Field of research:

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Summary:

This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]

Alternative names:

CAP70; CLAMP; NHERF-3; NHERF3; PDZD1

Species reactivity:

Human

Host:

Mouse

Target:

PDZK1

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human PDZK1 (NP_002605) produced in HEK293T cell.

Clone:

LBI2B4

Conjugation:

Unconjugated

Gene name:

PDZ domain containing 1

Symbol:

PDZK1

Pathway:

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Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:250~2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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