Product overview:

PRCC mouse monoclonal antibody,clone LBI5G7

Field of research:

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Summary:

This gene encodes a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X;1)(p11;q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle. [provided by RefSeq, Aug 2010]

Alternative names:

RCCP1; TPRC

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

PRCC

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 135-491 of human PRCC (NP_005964) produced in E.coli.

Clone:

LBI5G7

Conjugation:

Unconjugated

Gene name:

papillary renal cell carcinoma (translocation-associated)

Symbol:

PRCC

Pathway:

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Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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