Product overview:

IFNL1 mouse monoclonal antibody,clone LBI3D4

Field of research:

Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

Summary:

This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 28B (IL28B) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 2008]

Alternative names:

IL-29; IL29

Species reactivity:

Human

Host:

Mouse

Target:

IFNL1

Isotype:

IgG2b

Immunogen:

Human recombinant protein fragment corresponding to amino acids 20-200 of human IFNL1 (NP_742152) produced in E.coli.

Clone:

LBI3D4

Conjugation:

Unconjugated

Gene name:

interferon, lambda 1

Symbol:

IFNL1

Pathway:

Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

Function:

Druggable Genome, Secreted Protein, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

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