Product overview:

PCDH15 mouse monoclonal antibody,clone LBI7F10

Field of research:

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Summary:

This gene is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. It plays an essential role in maintenance of normal retinal and cochlear function. Mutations in this gene result in hearing loss and Usher Syndrome Type IF (USH1F). Extensive alternative splicing resulting in multiple isoforms has been observed in the mouse ortholog. Similar alternatively spliced transcripts are inferred to occur in human, and additional variants are likely to occur. [provided by RefSeq, Dec 2008]

Alternative names:

CDHR15; DFNB23; USH1F

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

PCDH15

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 160-400 of human PCDH15 (NP_001136235) produced in E.coli.

Clone:

LBI7F10

Conjugation:

Unconjugated

Gene name:

protocadherin-related 15

Symbol:

PCDH15

Pathway:

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Function:

Druggable Genome, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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