Product overview:

JAK3 mouse monoclonal antibody,clone LBI2B4

Field of research:

Chemokine signaling pathway, Jak-STAT signaling pathway, Primary immunodeficiency

Summary:

The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008]

Alternative names:

JAK-3; JAK3_HUMAN; JAKL; L-JAK; LJAK

Species reactivity:

Human

Host:

Mouse

Target:

JAK3

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 811-1124 of human JAK3 (NP_000206) produced in E.coli.

Clone:

LBI2B4

Conjugation:

Unconjugated

Gene name:

Janus kinase 3

Symbol:

JAK3

Pathway:

Chemokine signaling pathway, Jak-STAT signaling pathway, Primary immunodeficiency

Function:

Druggable Genome, Protein Kinase

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com