Product overview:

MST1R mouse monoclonal antibody,clone LBI1D12

Field of research:

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Summary:

This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta subunits, generated by proteolytic cleavage of a single-chain precursor. The beta subunit undergoes tyrosine phosphorylation upon stimulation by MSP. This protein is expressed on the ciliated epithelia of the mucociliary transport apparatus of the lung, and together with MSP, thought to be involved in host defense. Alternative splicing generates multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Jan 2016]

Alternative names:

CD136; CDw136; NPCA3; PTK8; RON; SEA

Species reactivity:

Human

Host:

Mouse

Target:

MST1R

Isotype:

IgG2a

Immunogen:

Human recombinant protein fragment corresponding to amino acids 25-304 of human MST1R (NP_002438) produced in E.coli.

Clone:

LBI1D12

Conjugation:

Unconjugated

Gene name:

macrophage stimulating 1 receptor

Symbol:

MST1R

Pathway:

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Function:

Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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