Product overview:

XDH mouse monoclonal antibody,clone LBI5D8

Field of research:

Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism

Summary:

Xanthine dehydrogenase belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Xanthine dehydrogenase can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism. [provided by RefSeq, Jan 2014]

Alternative names:

XAN1; XO; XOR

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

XDH

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 1-280 of human XDH (NP_000370) produced in E.coli.

Clone:

LBI5D8

Conjugation:

Unconjugated

Gene name:

xanthine dehydrogenase

Symbol:

XDH

Pathway:

Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com