Product overview:

GTF2H3 mouse monoclonal antibody,clone LBI4B5

Field of research:

Basal transcription factors, Nucleotide excision repair

Summary:

This gene encodes a member of the TFB4 family. The encoded protein is a subunit of the core-TFIIH basal transcription factor and localizes to the nucleus. The encoded protein is involved in RNA transcription by RNA polymerase II and nucleotide excision repair and associates with the Cdk-activating kinase complex. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 14. [provided by RefSeq, Dec 2012]

Alternative names:

BTF2; P34; TFB4; TFIIH

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

GTF2H3

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 1-241 of human GTF2H3 (NP_001507) produced in E.coli.

Clone:

LBI4B5

Conjugation:

Unconjugated

Gene name:

general transcription factor IIH subunit 3

Symbol:

GTF2H3

Pathway:

Basal transcription factors, Nucleotide excision repair

Function:

Druggable Genome, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com