Product overview:

M6PR mouse monoclonal antibody,clone LBI2F3

Field of research:

Lysosome

Summary:

Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. [UniProtKB/Swiss-Prot Function]

Alternative names:

CD-M6PR; CD-MPR; MPR-46; MPR 46; MPR46; SMPR

Species reactivity:

Human, Monkey, Mouse, Rat, Dog

Host:

Mouse

Target:

M6PR

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 27-185 of human M6PR (NP_002346) produced in E.coli.

Clone:

LBI2F3

Conjugation:

Unconjugated

Gene name:

mannose-6-phosphate receptor, cation dependent

Symbol:

M6PR

Pathway:

Lysosome

Function:

Druggable Genome, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com