Product overview:

ALDH4A1 mouse monoclonal antibody,clone LBI1H10

Field of research:

Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism, Metabolic pathways

Summary:

This protein belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of this enzyme is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2009]

Alternative names:

ALDH4; P5CD; P5CDh

Species reactivity:

Human, Mouse, Rat, Dog

Host:

Mouse

Target:

ALDH4A1

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 1-503 of human ALDH4A1 (NP_001154976) produced in E.coli.

Clone:

LBI1H10

Conjugation:

Unconjugated

Gene name:

aldehyde dehydrogenase 4 family member A1

Symbol:

ALDH4A1

Pathway:

Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism, Metabolic pathways

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500, IHC 1:500

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com