Product overview:

GTF3C4 mouse monoclonal antibody,clone LBI4A3

Field of research:

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Summary:

Essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin. Has histone acetyltransferase activity (HAT) with unique specificity for free and nucleosomal H3. May cooperate with GTF3C5 in facilitating the recruitment of TFIIIB and RNA polymerase through direct interactions with BRF1, POLR3C and POLR3F. May be localized close to the A box. [UniProtKB/Swiss-Prot Function]

Alternative names:

KAT12; TF3C-delta; TFIII90; TFIIIC90; TFIIIC290; TFIIICDELTA

Species reactivity:

Human, Monkey, Mouse, Rat

Host:

Mouse

Target:

GTF3C4

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 583-822 of human GTF3C4 (NP_036336) produced in E.coli.

Clone:

LBI4A3

Conjugation:

Unconjugated

Gene name:

general transcription factor IIIC subunit 4

Symbol:

GTF3C4

Pathway:

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Function:

Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500, IHC 1:750

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

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