Product overview:

IFNLR1 mouse monoclonal antibody,clone LBI3D5

Field of research:

Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

Summary:

The protein encoded by this gene belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Alternative names:

CRF2/12; IFNLR; IL-28R1; IL28RA; LICR2

Species reactivity:

Human

Host:

Mouse

Target:

IFNLR1

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 21-228 of human IFNLR1 (NP_734464) produced in E.coli.

Clone:

LBI3D5

Conjugation:

Unconjugated

Gene name:

interferon lambda receptor 1

Symbol:

IFNLR1

Pathway:

Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

Function:

Druggable Genome, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

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