Product overview:

UPP2 mouse monoclonal antibody,clone LBI10A3

Field of research:

Drug metabolism - other enzymes, Metabolic pathways, Pyrimidine metabolism

Summary:

Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates. [UniProtKB/Swiss-Prot Function]

Alternative names:

UDRPASE2; UP2; UPASE2

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

UPP2

Isotype:

IgG2b

Immunogen:

Full length human recombinant protein of human UPP2 (NP_775491) produced in HEK293T cell.

Clone:

LBI10A3

Conjugation:

Unconjugated

Gene name:

uridine phosphorylase 2

Symbol:

UPP2

Pathway:

Drug metabolism - other enzymes, Metabolic pathways, Pyrimidine metabolism

Function:

Request info at info@sobekbio.com

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com