Product overview:

BMP6 mouse monoclonal antibody,clone LBI8B11

Field of research:

Hedgehog signaling pathway, TGF-beta signaling pathway

Summary:

The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity. [provided by RefSeq, Jul 2008]

Alternative names:

VGR; VGR1

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

BMP6

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 21-374 of human BMP6 (NP_001709) produced in E.coli.

Clone:

LBI8B11

Conjugation:

Unconjugated

Gene name:

bone morphogenetic protein 6

Symbol:

BMP6

Pathway:

Hedgehog signaling pathway, TGF-beta signaling pathway

Function:

Adult stem cells, Cancer stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Secreted Protein, Stem cell relevant signaling - TGFb/BMP signaling pathway

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com