Product overview:

LILRB3 mouse monoclonal antibody,clone LBI3G9

Field of research:

B cell receptor signaling pathway

Summary:

This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Alternative names:

CD85A; HL9; ILT-5; ILT5; LILRA6; LIR-3; LIR3; PIRB

Species reactivity:

Human

Host:

Mouse

Target:

LILRB3

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 465-631 of human LILRB3 (NP_006855) produced in E.coli.

Clone:

LBI3G9

Conjugation:

Unconjugated

Gene name:

leukocyte immunoglobulin like receptor B3

Symbol:

LILRB3

Pathway:

B cell receptor signaling pathway

Function:

Druggable Genome, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

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