Product overview:

DNAJB4 mouse monoclonal antibody,clone LBI2F8

Field of research:

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Summary:

The protein encoded by this gene is a molecular chaperone, tumor suppressor, and member of the heat shock protein-40 family. The encoded protein binds the cell adhesion protein E-cadherin and targets it to the plasma membrane. This protein also binds incorrectly folded E-cadherin and targets it for endoplasmic reticulum-associated degradation. This gene is a strong tumor suppressor for colorectal carcinoma, and downregulation of it may serve as a good biomarker for predicting patient outcomes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]

Alternative names:

DjB4; DNAJW; HLJ1

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

DNAJB4

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 2-337 of human DNAJB4 (NP_008965) produced in E.coli.

Clone:

LBI2F8

Conjugation:

Unconjugated

Gene name:

DnaJ heat shock protein family (Hsp40) member B4

Symbol:

DNAJB4

Pathway:

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Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500~2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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