Product overview:

ITGAD mouse monoclonal antibody,clone LBI2F8

Field of research:

Regulation of actin cytoskeleton

Summary:

This gene belongs to the beta-2 integrin family of membrane glycoproteins, which are are composed of non-covalently linked alpha and beta subunits to form a heterodimer. It encodes the alpha subunit of the cell surface heterodimers and is involved in the activation and adhesion functions of leukocytes. The gene is located about 11kb downstream of the integrin subunit alpha X gene, another member of the integrin family. It is expressed in the tissue and circulating myeloid leukocytes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

Alternative names:

ADB2; CD11D

Species reactivity:

Human

Host:

Mouse

Target:

ITGAD

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 18-418 of human ITGAD (NP_005344) produced in E.coli.

Clone:

LBI2F8

Conjugation:

Unconjugated

Gene name:

integrin subunit alpha D

Symbol:

ITGAD

Pathway:

Regulation of actin cytoskeleton

Function:

Druggable Genome, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com