Product overview:

SPTAN1 mouse monoclonal antibody,clone LBI9C10

Field of research:

Tight junction

Summary:

Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. This gene encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells. The encoded protein has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in this gene are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2010]

Alternative names:

DEE5; EIEE5; NEAS; SPTA2

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

SPTAN1

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 1-147 of human SPTAN1 (NP_001123910) produced in E.coli.

Clone:

LBI9C10

Conjugation:

Unconjugated

Gene name:

spectrin alpha, non-erythrocytic 1

Symbol:

SPTAN1

Pathway:

Tight junction

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500~2000, IHC 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

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