Product overview:

KLF5 mouse monoclonal antibody,clone LBI6D2

Field of research:

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Summary:

This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. The encoded protein is a transcriptional activator that binds directly to a specific recognition motif in the promoters of target genes. This protein acts downstream of multiple different signaling pathways and is regulated by post-translational modification. It may participate in both promoting and suppressing cell proliferation. Expression of this gene may be changed in a variety of different cancers and in cardiovascular disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]

Alternative names:

BTEB2; CKLF; IKLF

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

KLF5

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 1 - 457 of human KLF5 (NP_001721) produced in E.coli.

Clone:

LBI6D2

Conjugation:

Unconjugated

Gene name:

Kruppel-like factor 5 (intestinal)

Symbol:

KLF5

Pathway:

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Function:

Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500~2000, IHC 1:5000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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