Product overview:

DCD mouse monoclonal antibody,clone LBI3F5

Field of research:

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Summary:

This antimicrobial gene encodes a secreted protein that is subsequently processed into mature peptides of distinct biological activities. The C-terminal peptide is constitutively expressed in sweat and has antibacterial and antifungal activities. The N-terminal peptide, also known as diffusible survival evasion peptide, promotes neural cell survival under conditions of severe oxidative stress. A glycosylated form of the N-terminal peptide may be associated with cachexia (muscle wasting) in cancer patients. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014]

Alternative names:

AIDD; DCD-1; DSEP; HCAP; PIF

Species reactivity:

Human

Host:

Mouse

Target:

DCD

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 20-110 of human DCD (NP_444513) produced in E.coli.

Clone:

LBI3F5

Conjugation:

Unconjugated

Gene name:

dermcidin

Symbol:

DCD

Pathway:

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Function:

Secreted Protein

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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