Product overview:

SYNE1 mouse monoclonal antibody,clone LBI1E10

Field of research:

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Summary:

This gene encodes a spectrin repeat containing protein expressed in skeletal and smooth muscle, and peripheral blood lymphocytes, that localizes to the nuclear membrane. Mutations in this gene have been associated with autosomal recessive spinocerebellar ataxia 8, also referred to as autosomal recessive cerebellar ataxia type 1 or recessive ataxia of Beauce. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Alternative names:

8B; ARCA1; C6orf98; CPG2; EDMD4; MYNE1; Nesp1; SCAR8; dJ45H2.2

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

SYNE1

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 1-285 of human SYNE1 (NP_598411) produced in E.coli.

Clone:

LBI1E10

Conjugation:

Unconjugated

Gene name:

spectrin repeat containing nuclear envelope protein 1

Symbol:

SYNE1

Pathway:

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Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:500

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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