Product overview:

NOS1AP mouse monoclonal antibody,clone LBI10F8

Field of research:

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Summary:

This gene encodes a cytosolic protein that binds to the signaling molecule, neuronal nitric oxide synthase (nNOS). This protein has a C-terminal PDZ-binding domain that mediates interactions with nNOS and an N-terminal phosphotyrosine binding (PTB) domain that binds to the small monomeric G protein, Dexras1. Studies of the related mouse and rat proteins have shown that this protein functions as an adapter protein linking nNOS to specific targets, such as Dexras1 and the synapsins. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2009]

Alternative names:

6330408P19Rik; CAPON; NPHS22

Species reactivity:

Human

Host:

Mouse

Target:

NOS1AP

Isotype:

IgG2a

Immunogen:

Human recombinant protein fragment corresponding to amino acids 1-196 of human NOS1AP (NP_055512) produced in E.coli.

Clone:

LBI10F8

Conjugation:

Unconjugated

Gene name:

nitric oxide synthase 1 adaptor protein

Symbol:

NOS1AP

Pathway:

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Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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