Product overview:

TBL1XR1 mouse monoclonal antibody,clone LBI2A8

Field of research:

Wnt signaling pathway

Summary:

This gene is a member of the WD40 repeat-containing gene family and shares sequence similarity with transducin (beta)-like 1X-linked (TBL1X). The protein encoded by this gene is thought to be a component of both nuclear receptor corepressor (N-CoR) and histone deacetylase 3 (HDAC 3) complexes, and is required for transcriptional activation by a variety of transcription factors. Mutations in these gene have been associated with some autism spectrum disorders, and one finding suggests that haploinsufficiency of this gene may be a cause of intellectual disability with dysmorphism. Mutations in this gene as well as recurrent translocations involving this gene have also been observed in some tumors. [provided by RefSeq, Mar 2016]

Alternative names:

C21; DC42; IRA1; MRD41; TBLR1

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

TBL1XR1

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human TBL1XR1 (NP_078941) produced in E.coli.

Clone:

LBI2A8

Conjugation:

Unconjugated

Gene name:

transducin (beta)-like 1 X-linked receptor 1

Symbol:

TBL1XR1

Pathway:

Wnt signaling pathway

Function:

Druggable Genome, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500~2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com