Product overview:

TFEC mouse monoclonal antibody,clone LBI2A9

Field of research:

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Summary:

This gene encodes a member of the micropthalmia (MiT) family of basic helix-loop-helix leucine zipper transcription factors. MiT transcription factors regulate the expression of target genes by binding to E-box recognition sequences as homo- or heterodimers, and play roles in multiple cellular processes including survival, growth and differentiation. The encoded protein is a transcriptional activator of the nonmuscle myosin II heavy chain-A gene, and may also co-regulate target genes in osteoclasts as a heterodimer with micropthalmia-associated transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]

Alternative names:

bHLHe34; hTFEC-L; TCFEC; TFE-C; TFEC-L; TFECL

Species reactivity:

Human

Host:

Mouse

Target:

TFEC

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human TFEC (NP_001018068) produced in E.coli.

Clone:

LBI2A9

Conjugation:

Unconjugated

Gene name:

transcription factor EC

Symbol:

TFEC

Pathway:

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Function:

Druggable Genome, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

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