Product overview:

NDUFA2 mouse monoclonal antibody,clone LBI5A5

Field of research:

Alzheimer's disease, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease

Summary:

The encoded protein is a subunit of the hydrophobic protein fraction of the NADH:ubiquinone oxidoreductase (complex 1), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane, and may be involved in regulating complex I activity or its assembly via assistance in redox processes. Mutations in this gene are associated with Leigh syndrome, an early-onset progressive neurodegenerative disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]

Alternative names:

B8; CD14; CIB8

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

NDUFA2

Isotype:

IgG2b

Immunogen:

Human recombinant protein fragment corresponding to amino acids 2-99 of human NDUFA2 (NP_002479) produced in E.coli.

Clone:

LBI5A5

Conjugation:

Unconjugated

Gene name:

NADH:ubiquinone oxidoreductase subunit A2

Symbol:

NDUFA2

Pathway:

Alzheimer's disease, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease

Function:

Request info at info@sobekbio.com

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com